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the study is to compare the intubating conditions between succinylcholine, the gold standard drug for rapid sequence induction and rocuronium after treatment with magnesium sulphate which makes the action of rocuronium similar to that of succinylcholine

Comparison of intubating conditions during rapid sequence induction between rocuronium with magnesium sulphate pretreatment and succinylcholine in patients undergoing elective surgery under general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/11/046959
Enrollment
150
Registered
2022-11-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Rocuronium after magnesium sulphate pretreatment: Magnesium sulphate will be given to the patient over 15 minutes before rocuronium and intubation is performed Intervention2: succinylch

Sponsors

ABVIMS Dr RML Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I & II Body mass index 18.5-24.9 kg/m2 Mallampati grade 1 & 2 surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: refusal of consent emergency surgery anticipated difficult airway pregnant or breastfeeding patients patients with hepatic, renal metabolic or neuromuscular disorders allergic to study drugs patients receiving drugs that influence neuromuscular functions

Design outcomes

Primary

MeasureTime frame
To compare the intubating conditions during rapid sequence intubation using Coopers criteriaTimepoint: intubating conditions will be graded as 8-9 : excellent 6-7 :good 3-5:fair 0-2:poor—

Secondary

MeasureTime frame
1.To study the hemodynamic parameters:heart rate,systolic,diastolic blood pressure amd mean arterial pressure,Sp02 in both groups at following intervals 2.To study the side effects : muscle pain, burning sensation,nausea,vomiting Timepoint: baseline (T0) before intubation (Ti) 1 minute after intubation(T1) 3 minutes after intubation (T3) 5 minutes after intubation(T5)—

Countries

India

Contacts

Public ContactNivedha

ABVIMS and Dr RML Hospital

nishakachru@yahoo.co.uk9810488435

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026