Health Condition 1: E669- Obesity, unspecified Health Condition 2: E116- Type 2 diabetes mellitus with other specified complications
Conditions
Interventions
None listed
Sponsors
Girisha Prajapat
Eligibility
Inclusion criteria
Inclusion criteria: 1. Obese patients with type-2 Diabetes mellitus. 2. Obese patients without type-2 Diabetes Mellitus. 3. Control group without any underlying disorder.
Exclusion criteria
Exclusion criteria: 1. Vision and hearing challenged subjects. 2. Pregnant woman. 3. Past history of neurological or psychiatric disorders. 4. Currently taking part in a weight-loss program. 5. Neurosurgery. 6. History of Seizures. 7. Alcohol or other drug dependence. 8. Regular use of anti-epileptic, sedative pills, antidepressants. 9. Known case of previous stroke.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Primary Objective: a. To assess the cognitive functions in obese subjects:- -by evaluating mini-mental state examination (MMSE) and montoreal cognitive assessment (MoCA). -by evaluating the blood levels of cognitive biomarker i.e. serum brain-derived neurotrophic factor (BDNF). 2. Secondary Objective: a. To compare the above objectives with age and sex matched healthy controls (non-obese subjects). Timepoint: After the sample collection process is completed, the BDNF level measurements using BDNF Elisa kit will be started. Sample collection will approximately take 4-6 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| If the relationship is established, artificial BDNF may be useful clinically in patients of endocrinolgy and psychology.Timepoint: 5 weeks | — |
Countries
India
Contacts
Public ContactGirisha Prajapat
All India Institute of Medical Sciences, Bathinda
Outcome results
None listed