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Evaluation of effect of Dexmedetomidine when used locally in controlling pain in patients with Retinal detachment undergoing Scleral Buckle surgery

Assessment of postoperative pain with local Dexmedetomidine in patients undergoing Scleral Buckling

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046934
Enrollment
105
Registered
2022-10-31
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H330- Retinal detachment with retinal break

Interventions

Intervention1: Drug Dexmedetomidine: Dexmedetomidine is a highly selective alpha-2 adrenoreceptor agonist. It provides dose dependent analgesic and sedative properties.Sample size will be divided into

Sponsors

Sankara eye Hospital Shimoga
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients with Rhegmetogenous retinal detachment undergoing Scleral Buckling or vitrectomy combined with encircling silicone band 2) Patients willing to give consent for study.

Exclusion criteria

Exclusion criteria: 1)Age below 18 years 2) History of Acute Ocular trauma 3) Open globe Injury 4) Scleral Thinning 5) Patients undergoing surgery under General Anesthesia 6) History of Sleep Apnea 7) Severe Cardiac Disease 8) Uncontrolled Diabetes 9) Drug abuse or any Contraindication to local anaesthesia 10) Clotting abnormalities 11) Impaired Mental Status 12) Chronic Obstructive Lung Disease

Design outcomes

Primary

MeasureTime frame
Duration of action of Dexmedetomidine when used as an additive to bupivacaine will be assessed at 1hr , 2hr, 4hr post surgeryTimepoint: Pain by Visual analog scale, Blood pressure, Pulse rate, will be assessed at 1hr, 2hr and 4 hr post surgery. Sleep quality will be assessed on the next morning after surgery .

Secondary

MeasureTime frame
Incidence of Systemic side effects of Dexmedetomidine.Timepoint: 1hr, 2hrs, 4hrs postoperatively;Time to post-op rescue analgesia and Total analgesic consumption in patients treated with DexmedetomidineTimepoint: 1hr, 2hrs, 4hrs postoperatively

Countries

India

Contacts

Public ContactDr Ritu Manwani

Sankara eye Hospital, Shimoga

drravshan@gmail.com9880312124

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026