Effects of cold anaesthesia during root canal treatment in diabetic Patients.

Glycemic Effects and Anesthetic Efficacy of Precooled-Lignocaine with and without Adrenaline During Inferior Alveolar Nerve Block in Diabetic Patients with Symptomatic Irreversible Pulpitis- An Observational study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046932

Enrollment

Registered

2022-10-31

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Pre cooled LA With and without adrenaline: 1.8ml of 2% lignocaine Hydrochloride given as inferior alveolar nerve block once Control Intervention1: Normal LA With and without adrenaline

Eligibility

Inclusion criteria

Inclusion criteria: 1. Mandibular molars with an endodontic pulpal diagnosis of symptomatic irreversible pulpitis. 2. Patients who had not taken any analgesics the day before and the day of the root canal procedure.

Exclusion criteria

Exclusion criteria: 1. Patients who refuse to give informed consent. 2. Teeth other than mandibular molars (incisors, canines, premolars). 3. Teeth with any resorptions, anatomy anomalies or perforations. 4. Patients taking medication for any systemic conditions other than DM. 5. Allergic to local anesthetics or any other drugs. 6. Conditions that influence the pain scores, and with presence of periapical radiolucency, swelling, and sinus tract. 7. Teeth with vertical fractures and periodontally compromised teeth. 8. Non-restorable teeth.

Design outcomes

Primary

Measure	Time frame
there will be no alteration in the glycemic index following administration of pre cooled LA in diabetic patientsTimepoint: immediate and post operative	—

Secondary

Measure	Time frame
Pre cooled LA will enhance the aesthetic effect in diabetic patientsTimepoint: post operative, 5 minutes and 15 minutes.	—

Countries

India

Contacts

Public ContactDr B Saravanakarthikeyan

SRM Institute of Science and Technology

researchmaha@gmail.com9381018598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026