Clinical evaluation of siddha formulation Koozhpaanda chooranam (internal) and Powthira Ranangalukku kalimbu (external) in the management of Paganthara moolam (fistula in ano)

An open, non â?? randomised, single arm, phase II, single centric clinical trial to evaluate the effectiveness of Siddha formulation Koozhpaanda chooranam (internal) and Powthira ranangalukku kalimbu (external) in the management of Paganthara moolam (Fistula in- Ano) among patients attending Ayothidoss pandithar hospital, National Institute of Siddha.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046913

Enrollment

Registered

2022-10-31

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K605- Anorectal fistula Health Condition 2: K928- Other specified diseases of the digestive system

Interventions

Intervention1: Koozhpaanda chooranam(internal) Powthira ranangalukku kalimbu(external): 1.Koozhpaanda chooranam 1 gram with hot water twice a day 2.Powthira ranangalukku kalimbu external for 48 days

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age: 20 to 60 years 2.Pus, blood and watery discharge from perianal and anal region 3.Sex: Male, Female and Transgender 4.Fistula tract within 4 cm 5.Patient who are willing to undergo kaaraseelai therapy 6.Willing to give specimen of blood for investigation whenever required 7.Willing to attend OPD or admission in IPD 8.Willing to take photograph before and after treatment 9.Patient already presenting with MRI fistulogram or willing to get the MRI from recognized laboratory

Exclusion criteria

Exclusion criteria: 1.Tuberculosis (Genito urinary tract). 2.Hepatitis B & C. 3.Hemophilia and bleeding disorders. 4.Pregnancy & Lactation. 5.Uncontrolled diabetes. 6.K/H/O Cardio vascular Diseases. 7.AIDS, Syphilis. 8.K/H/O Crohnâ??s disease. 9.High anal fistula and complicated fistula. 10.Rectal prolapse. 11.K/H/O Rectal carcinoma.

Design outcomes

Primary

Measure	Time frame
The measurement of the tract length before and after treatment will be assessed by PDAI and good outcome of PDAI score becoming zero.Timepoint: 1 year	—

Secondary

Measure	Time frame
secondary outcome is assessed by unit cutting timeTimepoint: 1 year	—

Countries

India

Contacts

Public ContactDrRMOHANA

NATIONAL INSTITUTE OF SIDDHA

dr.vetha@gmail.com9894782366

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026