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A Comparative Study on efficacy and safety of topical 2% clotrimazole cream daily twice application with oral fluconazole and topical 1% Piroctone olamine daily night application with oral fluconazole teice per week for total of 4 weeks in the treatment of extensive dermatophytosis

A Comparative Study on efficacy and safety of topical 2% clotrimazole cream with oral fluconazole and topical 1% Piroctone olamine with oral fluconazole in the treatment of extensive dermatophytosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046904
Enrollment
40
Registered
2022-10-31
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B354- Tinea corporis

Interventions

Intervention1: Topical clotrimazole with weekly flucanazole 300mg: Daily twice application of clotrimazole with weekly flucanazole 150 mg twice per week for Total duration 4 weeks Control Intervention

Sponsors

Department of DVL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: More than 20% BSA tinea corporis Positive KOH

Exclusion criteria

Exclusion criteria: With any comorbidites Pregnant and lactating mother

Design outcomes

Primary

MeasureTime frame
A Comparative Study on efficacy of topical 2% clotrimazole cream with oral fluconazole and topical 1% Piroctone olamine with oral fluconazole in the treatment of extensive dermatophytosisTimepoint: Clotrimazole topical application twice daily ,piroctone olamine daily night application followed by morning bath for four weeks,with oral flucanazole 150 mg twice weekly for four weeks

Secondary

MeasureTime frame
Compare the safety of clotrimazole and piroctone olamine with oral flucanazoleTimepoint: Weekly once for 4 weeks

Countries

India

Contacts

Public ContactR Sindhuja

Chengalpattu medical college and hospital

nivesekhar@gmail.com9486914293

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026