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"COMPARISION OF EFFECT OF TWO DRUGS ON INTRACRANIAL PRESSURE(pressure around brain) DURING KEY HOLE SURGERIES(procedure that permits visual examination of abdominal cavity with a scope ,inserted through small incision)"

"COMPARISON OF EFFECT OF PROPOFOL AND DEXMEDETOMIDINE ON INTRACRANIAL PRESSURE DURING LAPAROSCOPIC SURGERIESâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046896
Enrollment
60
Registered
2022-10-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: dexmedetomedine: dose of 0.5 mcg/kg/hr continuous infusion Intervention2: propofol: dose of 100mcg/kg/hr continuous infusion

Sponsors

INHS ASVINI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willing to participate in the study after giving due consent 2. Patients undergoing Elective Laparoscopic surgeries 3. Patients in ASA grade I & II 4. Patients over 18-65 years of age

Exclusion criteria

Exclusion criteria: 1. Patients with neurological, endocrine and psychiatry disorders 2. Patients with preexisting Opthalmic diseases and injuries 3. ASA classification more than II 4. Patients with known allergy to drugs used in study

Design outcomes

Primary

MeasureTime frame
Dexmedetomidine is effective in attenuating increase in intracranial pressure during creation of pneumoperitoneum compared to propofolTimepoint: 78 weeks—

Secondary

MeasureTime frame
propofol decreases the raise of intracranial pressure during creation of pneumoperitoneumTimepoint: 78 weeks—

Countries

India

Contacts

Public ContactDr vidhu Bhatnagar

maharastra university of health sciences

vizardsvids@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026