Comparison of balanced crystalloids versus normal saline for fluid resuscitation in sepsis patients .

Comparative study of Normal saline versus balanced crystalloids as fluid resuscitation in sepsis patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046875

Enrollment

365

Registered

2022-10-28

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A418- Other specified sepsis

Interventions

Intervention1: Balanced crystalloids: Balanced crystalloids are better choice of fluid in sepsis patients . Given Intravenous till the MAP is 30 mmHg Control Intervention1: Normal saline: Normal sali

Eligibility

Inclusion criteria

Inclusion criteria: Sepsis patient admitted to ICU

Exclusion criteria

Exclusion criteria: Patients with h/o pre existing cardiac dysfunction Patients with intracranial bleed or traumatic brain injury , hemorrhagic shock . Patients with pre existing hyperkalemia Patients with h/o chronic dialysis or renal transplant

Design outcomes

Primary

Measure	Time frame
In hospital mortality and ICU mortality ICU free days Number of mechanical ventilator free daysTimepoint: In hospital mortality and ICU mortality at 14 th and 28th day ICU free days Number of mechanical ventilator free days	—

Secondary

Measure	Time frame
Receipt of new renal replacement therapyTimepoint: 30 days	—

Countries

India

Contacts

Public ContactDr Vijaykumar H N

BMCRI

Vijay.bmc.ccm@gmail.com9886504680

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026