Health Condition 1: O720- Third-stage hemorrhage
Conditions
Interventions
Intervention1: Carbetocin 100 micrograms Intramuscular or Intravenous SINGLE DOSE (intravenous will be given in 500 ml of normal saline): In case of vaginal delivery, the SINGLE DOSE drug will be adm
Sponsors
Department of Obstetrics and Gynaecology
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 and above Women in early spontaneous labor Women planned for cesarean section (ELECTIVE). .Women undergoing emergency cesarean section in which oxytocin stopped for more than 1hour
Exclusion criteria
Exclusion criteria: Period of gestation Women undergoing labor induction or planned for induction Underlying cardiovascular, autoimmune, hepatic, or renal disease, Placenta accreta. Known allergy to oxytocin or related product. Patient on anticoagulation. Patient not in a sound state to give consent(eclampsia, psychiatric disorders) and epilepsy disorder Instrumental delivery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of women with blood loss of at least 500 ml or the use of additional uterotonic agents at 1 hour and up to 2 hours for women who continued to bleed after 1 hour.Timepoint: 1 hour and up to 2 hours for women who continued to bleed after 1 hour. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1] The proportion of women with blood loss â?¥500 ml at one hour (or two hours postpartum if the bleeding continues beyond one hour) 2] Blood loss in ml at one hour (or two hours postpartum if the bleeding continues beyond one hour) 3] The proportion of women receiving additional uterotonics at one hour (or two hours postpartum if the bleeding continues beyond one hour) 4] The proportion of women receiving additional uterotonics during follow up 5] The proportion of women receiving blood transfusion during follow up 6] The proportion of women with manual removal of placenta during follow up 7] The proportion of women having additional surgical procedures Timepoint: 1 hour and up to 24 hours | — |
Countries
India
Contacts
Public ContactDr Vishali
PGIMER, Chandigarh
Outcome results
None listed