Health Condition 1: E050- Thyrotoxicosis with diffuse goiter
Conditions
Interventions
Intervention1: NIL: NIL
Intervention2: NIL: NIL
Sponsors
AIIMS Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as Gravesâ?? disease in the age group of 18-65 years.
Exclusion criteria
Exclusion criteria: 1. All patients of Gravesâ?? disease who are pregnant. 2. All patients of Gravesâ?? disease who are breast feeding. 3. Patients with Hyperthyroidism diagnosis other than Gravesâ?? disease (toxic MNG and toxic adenomas) 4. Patients with coexisting thyroid cancer or suspicion of thyroid cancer. 5. Women planning a pregnancy within 6 months. 6. CAS (Clinical Activity Score) more than or equal to 3.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To establish a cut off of the turnover ratio for a successful 131-I ablation therapy dose selectionTimepoint: After completion of study. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the RAIU before the ATD treatment (if available) with RAIU after the ATD treatment and prior to 131-I ablation therapy.Timepoint: After completion of study.;To find association between RAIU values at various time intervals (2hr, 6hr and 24 hr).Timepoint: After completion of study.;To study the role of various other factors (history of anti-thyroid drugs intake, volume of gland, age, gender, FT3, FT4 & TSH Pre 131I therapy, 24hr RAIU, disease duration) in determining the outcome of the 131I therapy.Timepoint: After completion of study. | — |
Countries
India
Contacts
Public ContactDr Priyank Rajput
All India Institute of Medical Sciences
Outcome results
None listed