Homeopathic medicines to reduce pain at injection sites

Efficacy of Ledum palustre 200CH in preventing injection site pain and tenderness following COVID-19 vaccination: A double-blind, randomized, placebo-controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046839

Enrollment

218

Registered

2022-10-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ledum palustre 200CH: Intervention is planned as administering two doses of Ledum palustre 200CH half an hour prior and immediately after the COVID-19 vaccination. Each dose will consis

duration of therapy: 1 day Control Intervention1: Identical-looking placebos: This group will receive placebos, identical in appearance with the verum. Each dose will consist of 4 cane sugar globules

duration of therapy: 1 day

Eligibility

Inclusion criteria

Inclusion criteria: 1. Participants with an apparently healthy status with no major diseases 2. Age between 18 and 65 years 3. Participants of either sex or transgender 4. Participants providing written informed consent voluntarily

Exclusion criteria

Exclusion criteria: 1. Subjects with active or untreated malignancy or recovered from malignancy. 2. Vulnerable population – unconscious, ambulatory, too sick for consultation, differently abled, terminally or critically ill patients, mentally incompetent people. 3. Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life or any organ failure. 4. Pregnant and puerperal women, lactating mothers. 5. Self-reported immune-compromised state. 6. Substance abuse and/or dependence

Design outcomes

Primary

Measure	Time frame
Intensity of injection site pain and tenderness in both groups measured using a 0-100 mm visual analogue scale (VAS)Timepoint: Day 1, day 2, day 3, day 5, day 7, then once weekly until 1 month	—

Secondary

Measure	Time frame
NilTimepoint: NA	—

Countries

India

Contacts

Public ContactSubhasish Ganguly

D N De Homoeopathic Medical College and Hospital

satya.naskar@gmail.com8981859153

Outcome results