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Nebulized Lignocaine versus Nebulized Dexmedetomidine in blunting stressor response to intubation

Comparative evaluation of Nebulized Lignocaine with that of Nebulized Dexmedetomidine in blunting haemodynamic response to intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046812
Enrollment
60
Registered
2022-10-26
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulized lignocaine: 4% Lignocaine hydrochloride solution via a facemask and cirrus nebulizer with oxygen at 8 L /min in preoperative room.recordings of HR, SBP, DBP and MAP before n

Sponsors

PASUPALA SUBBA KAVYA SREE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 60 years for both sexes belonging to ASA class 1,2 posted for elective surgeries under GA.

Exclusion criteria

Exclusion criteria: 1. History of allergies to local anaesthetic agents or to the study drug. 2. Refusal by patient to participate in study 3. Patients of ASA class 3 and 4. 4. Patients with anticipated difficult airway. 5. Baseline heart rate 6. Patients weighing

Design outcomes

Primary

MeasureTime frame
To find out the changes in hemodynamic variables (in terms of 20% rise from baseline values) in two groups of patients belonging to both the genders undergoing elective surgeries under general anaesthesia with endotracheal intubation.Timepoint: upto 15 minutes post intubation

Secondary

MeasureTime frame
To study any adverse effects of the drug such as bradycardia, hypotenstion and post operative sedation and sore throat.Timepoint: upto 24 hrs postoperatively

Countries

India

Contacts

Public ContactPASUPALA SUBBA KAVYA SREE

IMS AND SUM HOSPITAL

dr.silu76@gmail.com9566841303

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026