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Comparing how effective is Platelet Rich Fibrin and Advanced-Platelet Rich Fibrin membranes incorporated with antibiotics against bacteria

Comparative evaluation of the antibacterial efficacy of PRF and A-PRF membranes incorporated with antibiotics as a slow release biologic device â?? An in vitro study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046803
Enrollment
9
Registered
2022-10-26
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: advanced platelet rich fibrin: advanced platelet rich fibrin will be prepared using 10 cc blood and incorporated with antibiotics against periodontal bacteria over 7 days Control Interv

Sponsors

Dr Mugdha Mangaonkar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patients willing to participate Normal haemogram

Exclusion criteria

Exclusion criteria: A) Patients with any systemic diseases. B) Pregnant and lactating women. C) Smokers or any other deleterious habits D) Immune and mental disorders

Design outcomes

Primary

MeasureTime frame
to comparatively evaluate the antibacterial efficacy of PRF and A-PRF membranes incorporated with Metronidazole Clindamycin and Amoxicillin trihydrate against Fusobacterium nucleatum Prevotella intermedia and streptococccus sanguisTimepoint: 7 days—

Secondary

MeasureTime frame
to determine the minimum inhibitory concentration of Metronidazole Clindamycin and Amoxicillin trihydrate against Fusobacterium nucleatum Prevotella intermedia and streptococccus sanguisTimepoint: 1 day—

Countries

India

Contacts

Public ContactDr Mugdha Mangaonkar

MGM dental college and hospital Kamothe

khistesujeet@gmail.com9833908511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026