Management of Grahani Roga (A digestive system disorder like IBS) through Ayurveda Medicine

A clinical study to evaluate the effectiveness of Gandhaka Rasayana in the management of Grahani Roga

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046792

Enrollment

Registered

2022-10-26

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K582- Mixed irritable bowel syndrome

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: a) Patients having age between 18 – 65 years of either sex. b) Patients having following symptoms of Grahani Roga (Amavastha) – 1. Atisrishtam Vibaddham Va Dravam (Irregular bowel habits) 2. Ama Mala Pravritti (Sticky stool) I. Durgandhita Mala Pravritti (Fowl Smelling stool) II. Pichchhila Mala Pravritti (Mucous mixed stool) 3. Vibaddha (Constiaption) 4. Dravam (Loose Stool) 5. Udara Shoola (Abdominal pain) 6. Udara Gaurava (Heaviness in abdomen) 7. Ashthi-Parva ruka (Bodyache) 8. Aruchi (Anorexia) 9. Atopa (Bloating) 10. Tikta-Amla Udgar/Vidaha (Acid eructation/Burning sensation in Abdomen) 11. Jwara (Fever) 12. Karshya/ Balakshaya (Weakness) c) Patient willing to sign the consent form

Exclusion criteria

Exclusion criteria: a) Age below 18 and above 65 years. b) Patients suffering from Intestinal tuberculosis, Severe ulceration in stomach. c) Patients with complicated and chronic Renal or Liver disorders like Nephrotic syndrome, Hepatitis, Chronic infections and other serious diseases. d) Patients on prolonged ( >6 weeks) medication with corticosteroids, antidepressants, anticholinergics, etc. or any other drugs. e) Pregnant women and lactating mothers. f) Patients having uncontrolled Diabetes Mellitus or uncontrolled Hypertension. g) Systemic illness like Tuberculosis, Carcinoma and Endocrine disorders. h) Patient having the symptoms of Acute M.I., Unstable Angina or CCF. i) Who have completed participation in other clinical trial during the past six months. j) Alcoholics and/or drug abusers. k) Any other condition which the Principal Investigator thinks may jeopardize for study.

Design outcomes

Primary

Measure	Time frame
BOWEL FREQUNCY CONSISTENCY AND MOVEMENT WITH ABDOMINAL PAIN AND BLOATING WILL BE ASSESSED AS PRIMARY OUTCOME ALONG WITH EFFECTIVENESS OF GANDHAKA RASAYANA IN THE MANAGEMENT OF GRAHANI ROGA.Timepoint: 45 DAYS	—

Secondary

Measure	Time frame
1. To evaluate the safety, sustainability and adverse drug reaction of trial drug. 2. To find out the prevalence of symptoms/diseases like IBS, IBD, amoebiasis, ulcerative colitis and many other diseases which are having clinical similarities with Grahani Roga and effectiveness of trial drug on them.Timepoint: 45 DAYS	—

Countries

India

Contacts

Public ContactDr Vinod Kumar Gautam

DR SARVEPALLI RADHAKRISHNAN RAJASTHAN AYURVED UNIVERSITY JODHPUR

drpramodmishra4@gmail.com9001009793

Outcome results