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Driving pressure guided positive end expiratory pressure (PEEP) vs fixed PEEP in preventing lung collapse

A comparative study of driving pressure guided individualized versus fixed positive end expiratory pressure on incidence of postoperative lung atelectasis in patients undergoing laparoscopic surgeries in trendelenburg position : A double blinded random

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046764
Enrollment
82
Registered
2022-10-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system

Interventions

Intervention1: Driving pressure guided positive end expiratory intra operatively: Driving pressure guided PEEP (PLAT-PEEP) will be used to find out the individualized PEEP using the incremental PEEP p

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients undergoing laparoscopic urological and gynaecological surgeries. 2) ASA PS 1 & 2 patients

Exclusion criteria

Exclusion criteria: 1) Patients refusal to participate in the study 2) Previous thoracic surgeries or massive blood loss >40ml/Kg 3) Patients with ARDS / lung injury / COPD / chronic lung disease. 4) Recent history of upper respiratory tract infection/ history of bronchial asthma 5) Significant cardiac, renal or hepatic disease. BMI 30 Kg/m2

Design outcomes

Primary

MeasureTime frame
To identify whether an individualized PEEP guided by driving pressures can reduce the magnitude of postoperative ( 30 minutes after extubation) lung atelectasis as compared to a fixed PEEP assessed by change in modified lung ultrasound scoreTimepoint: 24 hours after extubation of the patient—

Secondary

MeasureTime frame
Post operative oxygen requirementTimepoint: Post operative period—

Countries

India

Contacts

Public ContactSudeep Takoor

All India Institute of Medical Sciences

drmamta12@gmail.com9818113061

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026