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Measuring Oxygen extraction in septic shock and compare it with lactate clearance

Correlation of Oxygen Extraction and Carbon Dioxide Production using Indirect Calorimetry with Lactate Clearance in Septic Shock

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/10/046742
Enrollment
50
Registered
2022-10-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B999- Unspecified infectious disease

Interventions

None listed

Sponsors

Dayanand Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: are mechanically ventilated and suspected to be in septic shock as per Sepsis-3 definition which involves lactate levels greater than or equal to 2 mmol/L and vasopressor use

Exclusion criteria

Exclusion criteria: Extracorporeal therapy, FIO2 requirement > 85% Changes of ventilator settings during IC measurement Refusal of informed consent

Design outcomes

Primary

MeasureTime frame
Measuring Oxygen extraction using indirect calorimetry and comparing the trend with lactate clearanceTimepoint: baseline and at 6 hours—

Secondary

MeasureTime frame
Correlation of VO2, VCO2 with Clinical, Biochemical parameters and OutcomeTimepoint: 0, 7, 28 days—

Countries

India

Contacts

Public ContactJeevan Kumar

Dayanand Medical College and Hospital

dmchccm@gmail.com9814176565

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026