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Comparison of Dexmedetomidine Infusion V/S Normal Saline on Emergence Agitation and Quality of Recovery After Laparoscopic Surgery

Comparison of Intra Operative Infusion of Dexmedetomidine V/S Placebo on Post Operative Emergence Agitation and Quality of Recovery After Elective Laparoscopic Surgery - A Prospective Randomized Double Blind Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046741
Enrollment
90
Registered
2022-10-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Intra venous infusion of 2 microgram/ml (in 50 ml syringe) at 0.4 microgram/kg/hour for 2 hours Control Intervention1: Normal Saline: 50ml for 2 hours

Sponsors

Sparsh Foundations
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient who give informed consent 2. Adult patient of both genders 3. Age >18 And 4.American society of anaesthesiologists physical status 1 and 2 5.patients Scheduled for elective laparoscopic surgery <2 hours and requiring general anaesthesia with direct laryngoscopy and endotracheal intubation.

Exclusion criteria

Exclusion criteria: 1. Refusal by the patient to be part of the study. 2. American society of anaesthesiologists physical status 3 and 4 3. known or suspected allergy to alpha 2 adrenergic agonist or NSAIDS 4. Use of MAO inhibitors or Adrenergic Blocking Drugs. 5. Second or third degree heart block 6. Impaired Cognition 7. Chronic Use of Anti Psychotic Medications. 8. Renal Failure 9. Liver Disease 10. BMI > 30 kg/m2 11. Pregnant Women

Design outcomes

Primary

MeasureTime frame
Emergence agitation will be measured using Rikerâ??s sedation agitation scaleTimepoint: From time zero (when inhalational agent sevoflurane is stopped) till 2 minutes after extubation—

Secondary

MeasureTime frame
1.post operative pain will be assessed using VAS scoring system 2.post operative nausea and vomiting using 4 point nausea vomiting scale 3. cough will be assessed using 4 point cough scale Timepoint: 1.post operative pain will be assessed using VAS scoring system 5, 10, 15, 30, 60, 90, 120 minutes after surgery in post operative ward. 2.post operative nausea and vomiting using 4 point nausea vomiting scale 5, 10, 15, 30, 60, 90, 120 minutes after surgery in post operative ward. 3. cough will be assessed using 4 point cough scale 5, 10, 15, 30, 60, 90, 120 minutes after surgery in post operative ward.—

Countries

India

Contacts

Public ContactDr Nainika Raj

Sparsh superspecialty Hospital

jyothishankar2908@gmail.com9845397504

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026