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Comparison of effectiveness of postoperative pain relief in general anaesthesia between opioid group and without opioid using nerve block, continuous intravenous lidocaine and magnesium injection.

"Comparision of postoperative analgesic efficacy of opioid free anaesthesia with intravenous magnesium, lidocaine infusion and erector spinae block versus opioid based anaesthesia in laparoscopic abdominal surgeries - A randomized controlled trial".

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046738
Enrollment
66
Registered
2022-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Along with GA agents, intravenous magnesium, lidocaine infusion and erector spinae block: GA agents + Magnesium 2g (bolus dose) slow IV and Lidocaine 1.5mg/kg/hr infusion —— maintenance

Sponsors

AARUPADAI VEEDU MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I and ASA II Patients 2. Age between 18 years to 60 years 3. Patient scheduled for elective laparoscopic abdominal surgeries - appendicectomy and cholecystectomy.

Exclusion criteria

Exclusion criteria: 1. Patient not willing to participate in the study. 2. ASA III and above. 3. Patients with coagulation abnormality. 4. Patients with hepatic, cardiac, liver and renal illnesses. 5. BMI > 35kg/m2. 6. Pregnant women. 7. Hypersensitivity to any of the drugs used (Lidocaine, bupivacaine, propofol). 8. Surgeries lasting more than 2 hours. 9. Emergency surgeries. 10. Infection at the site of fascial plane block.

Design outcomes

Primary

MeasureTime frame
Increased post operative analgesia duration in Opioid free groupTimepoint: 12 - 24 hours postoperative period—

Secondary

MeasureTime frame
Haemodynamic stability Less postoperative sedation Less incidence of nausea, vomiting, pruritusTimepoint: Intraoperative perioperative, 0-24 hours postoperative period—

Countries

India

Contacts

Public ContactDr Ezhil Rajan MBBS MD DA DNB

AARUPADAI VEEDU MEDICAL COLLEGE AND HOSPITAL

ezhilrajan96@gmail.com9843030074

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026