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Bleach method versus conventional Ziehl-Neelson stain for the detection of acid fast bacilli in extrapulmonary tuberculous aspirates

Modified bleach method versus conventional Ziehl-Neelson stain for the detection of acid fast bacilli in extrapulmonary tuberculous aspirates â?? a study of diagnostic accuracy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/10/046725
Enrollment
146
Registered
2022-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A182- Tuberculous peripheral lymphadenopathy Health Condition 2: A182- Tuberculous peripheral lymphadenopathy

Interventions

Control Intervention1: Nil: Nil

Sponsors

Rohilkhand Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Fine needle aspirates and body fluids from all patients clinically suspected of tuberculosis with extra-pulmonary involvement, of any age and gender, referred to or received in the Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly for cytological examination, during the study period, till the appropriate sample size is achieved.

Exclusion criteria

Exclusion criteria: - Samples inadequate for reporting. - Initiation of anti-tubercular therapy within the last 3 months.

Design outcomes

Primary

MeasureTime frame
To compare the sensitivity of the modified bleach method of concentration with the conventional Ziehl-Neelson method of staining for detection of tubercle bacilli in suspected tuberculous aspirates from extra-pulmonary sites.Timepoint: Baseline diagnostic investigation at the time of presentation, before the initiation of antitubercular treatment (ATT)

Secondary

MeasureTime frame
â?¢ To compare the grading of AFB positivity by modified bleach method of concentration with the conventional ZN method of staining.Timepoint: Baseline diagnostic investigation at the time of presentation before the initiation of anti-tubercular treatment (ATT)

Countries

India

Contacts

Public ContactDr Saudamini Agarwal

Rohilkhand Medical College and Hospital

drnitesh@gmail.com9997872559

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026