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comparison of two drugs for oral diseases that can be convert into cancer.

COMPARISON OF THE EFFECTIVENESS OF INJECTABLE PLATELET RICH FIBRIN VS INJECTABLE TRIAMCINOLONE IN PATIENTS WITH SYMPTOMATIC ORAL LICHEN PLANUS: A RANDOMIZED CONTROL STUDY

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046681
Enrollment
108
Registered
2022-10-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere

Interventions

Intervention1: triamcinolone injectable: on left side of buccal mucosa triamcinolone acetonide will be injected diluted with local anesthatic in 1:1 ratio. Control Intervention1: injectable platelate

Sponsors

faculty of dental sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient aged between 18-65 years of age 2. Patients suffering from DC/TMD diagnostic criteria for MPDS 3. Patients presenting with pain, trismus and clicking without any radiological and pathological findings.

Exclusion criteria

Exclusion criteria: 1. Patient under the age of 18 and above 65 years 2. Patients with recent TMJ dislocation, hairy surface, radiculopathy, or other neurological deficits. 3. Patients on any medication for MPDS 4. Patients having any cardiac surgery or any other systemic illness. 5. Pregnancy or breastfeeding women 6. Patient diagnose with other orofacial pain disorders.

Design outcomes

Primary

MeasureTime frame
1. Reduction in the lesion area. Timepoint: baseline and after 4 weeks

Secondary

MeasureTime frame
Changes in morphological aspects of the lesion will be assessed by orally examining before and after treatment (according to the Thongprasom score)Timepoint: baseline and after 4 weeks

Countries

India

Contacts

Public ContactDr NIsha Maddheshiya

Banaras Hindu University

adit@bhu.ac.in09451525522

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026