Comparing the efficacy of Three Adjuvant Anti-Inflammatory agents in Minor Facial Surgery- A randomised controlled trial.

Comparison of efficacy as an adjuvant in anti-inflammatory therapy of Trypsin & Chymotrypsin , Serratiopeptidase and Prednisolone in various facial injuries and minor oral surgical procedures â??A Randomized Control Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046663

Enrollment

172

Registered

2022-10-20

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth Health Condition 2: K011- Impacted teeth

Interventions

Intervention1: MANAGEMENT OF SOFT TISSUE INJURIES OF FACE,SURGICAL REMOVAL OF TEETH ,DENTAL IMPLANT PLACEMENT ,OPEN REDUCTION AND FIXATION OF SINGLE FACIAL FRACTURE: MINOR ORAL SURGICAL PROCEDURES AND

Eligibility

Inclusion criteria

Inclusion criteria: 1. Participants with ASA criteria 1 & 2 2. Participants with no significant medical problems 3.Participants who were able to read and understand Visual analog scale scoring

Exclusion criteria

Exclusion criteria: -history of any allergic reaction to NSAIDs -history of peptic ulcers or GI bleeding -history of renal or hepatic disease -hemorrhagic disorders -pregnancy and lactation -currently taking anti-inflammatory agents, anticoagulants, lithium, cyclosporine, and methotrexate -concurrent treatment with immunosuppressants, corticosteroids

Design outcomes

Primary

Measure	Time frame
- Swelling - Pain - Mouth opening ability - - Assessment of erythema, local irritation, discharge and induration - Wound healing Timepoint: All outcome are measured at preop , day 0 , 3 , 5 and 7	—

Secondary

Measure	Time frame
swelling ,pain ,Wound healing.Timepoint: All outcome are measured at preop , day 0 , 3 , 5 and 7	—

Countries

India

Contacts

Public ContactDrAbinaya Subramanian

SRM INSTITUTE OF MEDICAL HEALTH AND SCIENCES, SRM UNIVERSITY

abinayas@srmist.edu.in8939014999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026