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Comparison of doses of Esmolol for decreasing stress response to Intubation

Efficacy Of Three Different Doses Of Esmolol For Attenuation Of Hemodynamic Stress Response To Laryngoscopy And Endotracheal Intubation In Surgeries Under General Anaesthesia-A Controlled Randomized Comparative Study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046653
Enrollment
54
Registered
2022-10-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration

Interventions

Intervention1: Attenuation of Hemodynamic response to Endotracheal Intubation by drug(Esmolol 0.8mg/kg ,1mg/kg and 1.5mg/kg): Pt will be divided into three groups .These groups will receive different

Sponsors

ABVIMS AND DR RML HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society Of Anesthesiologists(ASA)Physical Status I And II Patients. 2. Either Sex. 3. Age:20 to 50 years. 4. Elective Surgical procedure.

Exclusion criteria

Exclusion criteria: 1.Known sensitivity to any study drug. 2.Pregnant females. 3.Patient with chronic hypertension and diabetes mellitus. 4.Patient with history of cardiac or respiratory disease. 5.Patient with anticipated difficult airway. 6.Patient with impaired kidney or liver function. 7. Patient on Beta Blockers.

Design outcomes

Primary

MeasureTime frame
Hemodynamic Parameters To Laryngoscopy And Endotracheal Intubation (HR, SBP, DBP, MAP)Timepoint: Baseline(at arrival in ot). 1 minute after Laryngoscopy and Intubation 3 minutes after Laryngoscopy and Intubation 5 minutes after Laryngoscopy and Intubation—

Secondary

MeasureTime frame
Biochemical markers of stress response ( serum cortisol and blood glucose levels)Timepoint: Baseline(at arrival in ot). 5 minutes after Laryngoscopy and Intubation.—

Countries

India

Contacts

Public ContactDr Pooja Singla

ABVIMS AND DR. RML HOSPITAL, NEW DELHI

lalitachaudhary055@gmail.com9968299710

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026