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Para-aortic lymph node metastasis in non-pancreatic periampullary cancer

Incidence, predictive factors and post-operative outcomes of patients undergoing pancreatoduodenectomy for non-pancreatic periampullary cancer with para-aortic lymph node metastases - a prospective and retrospective study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/10/046605
Enrollment
100
Registered
2022-10-18
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C241- Malignant neoplasm of ampulla of Vater

Interventions

None listed

Sponsors

The Jawaharlal Institute of Postgraduate Medical Education Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA All patients who are more than 18 years with non-pancreatic periampullary carcinoma who underwent pancreatoduodenectomy or to undergo pancreatoduodenectomy.

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA 1. Pregnancy or lactating women. 2. Systemic metastasis 3. PD after neoadjuvant chemotherapy 4. Intraoperative distant metastases 5. R2 resection

Design outcomes

Primary

MeasureTime frame
To assess the incidence of para-aortic lymph node metastases in patients with non-pancreatic periampullary carcinoma who underwent pancreatoduodenectomy or to undergo pancreatoduodenectomy Timepoint: Baseline, 7 days, 30 days—

Secondary

MeasureTime frame
1)To evaluate the predictive factors of para-aortic lymph node metastasis: • Diameter of PALN • Etiology • Tumor size • Number of lymph node & Lymph node ratio • Perineural invasion & Angioinvasion • Positive resected margin • Time to surgery from diagnosis • CEA & CA19-9 2) To evaluate the short-term postoperative outcomes like: • Clavien-Dindo score • Post-operative pancreatic fistula • Hemorrhage • Biliary fistula • 30- & 90-days mortality Timepoint: Baseline, 7 days, 30 days—

Countries

India

Contacts

Public ContactDr Gnaneshvar Manivannan

The Jawaharlal Institute of Postgraduate Medical Education & Research

raj.jipmer@gmail.com9443292979

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026