A comparative study between chlorhexidine coated absorbable and non chlorhexidine coated suture in controlling infections after surgical extractions

A comparative assessment on the efficacy of chlorhexidine coated polyglactin 910 versus non coated polyglactin 910 sutures after surgical extraction in reducing postoperative infections - A prospective study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046594

Enrollment

Registered

2022-10-18

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: K030- Excessive attrition of teeth Health Condition 3: K011- Impacted teeth Health Condition 4: K041- Necrosis of pulp Health Condition 5: K046- Periapical abscess with sinus

Interventions

Intervention1: chlorhexidine coated poylglactin 910 sutures: polyglactin 910 sutures infused with 0.2% chlorhexidine Sutures will be placed immediately post extraction and will be observed at post op

Eligibility

Inclusion criteria

Inclusion criteria: Healthy adult patients Patients with Normal TMJ function Patients with adequate mouth opening Patients requiring extractions with surgical exposure requiring flap elevation and buccal bone guttering

Exclusion criteria

Exclusion criteria: Patients not willing to give consent Patients with systemic co morbidities Pregnant and lactating women or on oral contraceptives Patients with a known history of allergy to chlorhexidine Patients who have taken antibiotics prior , in a span of 2-3 weeks for any head and infections including upper respiratory tract infections Chronic smokers Patients with poor oral hygiene Patients with mental deficit / mental retardation Patients requiring more than three sutures for approximation

Design outcomes

Primary

Measure	Time frame
Presence or absence of infection at the surgical siteTimepoint: Post Operative Day 1 , 4 and 7	—

Secondary

Measure	Time frame
to assess and compare the efficacy of chlorhexidine coated polyglactin 910 in reducing pain , erythema , trismus , swelling and wound dehiscence against that of non coated polyglactin 910Timepoint: post operative day 1,4,7;to assess the ability of chlorhexidine coated polglactin 910 in controlling the colony forming units of bacteria against non coated polyglactin 910Timepoint: post operative day 7;to assess the presence of causative organism behind surgical site infectionTimepoint: post operative day 7	—

Measure

Time frame

to assess and compare the efficacy of chlorhexidine coated polyglactin 910 in reducing pain , erythema , trismus , swelling and wound dehiscence against that of non coated polyglactin 910Timepoint: post operative day 1,4,7;to assess the ability of chlorhexidine coated polglactin 910 in controlling the colony forming units of bacteria against non coated polyglactin 910Timepoint: post operative day 7;to assess the presence of causative organism behind surgical site infectionTimepoint: post operative day 7

—

Countries

India

Contacts

Public ContactDR SOUMI SAMUEL

A B SHETTY MEMORIAL INSTITUTE OF DENTAL SCIENCES

drsoumisamuel@nitte.edu.in9880834711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026