None listed
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: Children who have received COVID-19 vaccination with 2nd dose between 2 to 3 months from the date of enrolment. Group 1: Participants who have received BCG vaccine at birth or infancy. Operation definition of BCG vaccinated children in the primary objective: presence of BCG scar over left arm. A separate exploratory analysis will also be done which will include children without BCG scar who have a positive history of BCG vaccination taking into consideration the cases of scar negative BCG vaccination Group 2: Participants who have not received BCG vaccine at birth or infancy.
Exclusion criteria
Exclusion criteria: 1) Known active case or a history of Mycobacterium tuberculosis infection. 2) Children with diagnosed or suspected immunodeficiency states-primary or secondary. 3) Children with suspected or confirmed malignancy. 4) Children with history of blood transfusion, intravenous immunoglobin, steroids or immunosuppressive drugs in the last three months. 5) Fever within past 72 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of COVID-19 antibody titres between BCG vaccinated & unvaccinated groupsTimepoint: at baseline,3 and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| comparison of T cell marker CD45RO in both BCG vaccinated & unvaccinated children comparison of covid 19 antibody titres in children with low & normal BMITimepoint: At baseline | — |
Countries
India
Contacts
Public ContactDr Pratibha
UCMS and GTB Hospital
Outcome results
None listed