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To check difference in laser and steroid therapy on Oral lichen planus patients .

Comparative Effectiveness of Photodynamic Therapy (660nm)Vs Triamcinolone acetonide 0.1% in Symptomatic Oral Lichen planus patients and assessment of IL-1beta,IL-6,TNF-alpha and MDA Biomarkers:A Randomized Controlled Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046519
Enrollment
60
Registered
2022-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K137- Other and unspecified lesions of oral mucosa

Interventions

Intervention1: PHOTODYNAMIC THERAPY: Localized photobiomodulation with low-level diode laser equipment and along with the topical application of toluidine blue on the lesion acting as a photosensitize

Sponsors

Sakshi Batra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i.Participants of both gender and age between 18 years to 60 years, will be diagnosed with symptomatic lesions of reticular, atrophic, and erosive oral lichen planus based on clinical, histopathological criteria by WHO. ii. Patients who give informed consent after explaining the treatment type will be included in the study

Exclusion criteria

Exclusion criteria: i. Patients with any other Potentially Malignant Oral Disorders (PMOD) will be excluded. ii. Pregnant females and breastfeeding mothers will be excluded. iii. Patients having photosensitivity will be excluded. iv. Patients with a history of corticosteroids, NSAIDs, or any other treatment in the last 30 days will be excluded. v. Patients with other systemic diseases or illnesses will be excluded.

Design outcomes

Primary

MeasureTime frame
Pain and burning sensationTimepoint: baseline,1 month,2nd month,3rd month

Secondary

MeasureTime frame
size of the lesionTimepoint: baseline,1month,2nd month,3rd month.

Countries

India

Contacts

Public ContactDr Adit

BANARAS HINDU UNIVERSITY

adit@bhu.ac.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026