Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified
Conditions
Interventions
Intervention1: Early mobilisation and inspiratory muscle training: The early active mobilisation and inspiratory muscle training will be initiated as soon as weaning difficulties have been acknowledg
Sponsors
Pentamed Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Age > 18 years. Intubated. Receiving Mechanical Ventilation in ICU > 48 hours. COPD Patients of type 2 respiratory failure. Patients with Maximum inspiratory pressure (PIMAX): 15 to 30 cm H2O. Rapid shallow breathing index (RSBI): 60â??105
Exclusion criteria
Exclusion criteria: Unable to perform test manoeuvre. Any pre-existing neuromuscular disease. Any Associated Pulmonary Disease. Acute coronary syndrome (ACS). Haemoptysis. Spinal cord injury above T8. Any skeletal pathology that impairs chest wall movements such as severe kyphoscoliosis congenital deformities or contractures. Poor general prognosis or anticipated fatal outcome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weaning success. Duration of mechanical ventilation (days). Reintubation. Tracheostomy. Length of ICU stay and hospital stay (days). Mortality. Adverse events in patients. Timepoint: Till hospital discharge/death of the patient, whatever comes first | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial blood gas (ABG). Inspiratory muscle strength (Plmax). Rapid shallow breathing index (RSBI) i.e Lung compliance associated with adequate gas exchange and lower respiratory rate. Measurement of diaphragm thickness and function by ultrasound. Timepoint: Till hospital discharge/death of the patient, whatever comes first | — |
Countries
India
Contacts
Public ContactSajad Ahmad
Jamia Hamdard
Outcome results
None listed