A clinical trial to study the effect of drug, buprenorphine by administering through 2 route(intravenous and epidural) in patient for pain management following abdominal surgery

A prospective randomized study to compare haemodynamic changes and postoperative outcome of intravenous buprenorphine versus epidural buprenorphine in patients undergoing abdominal surgeries under general anaesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046510

Enrollment

Registered

2022-10-14

Start date

Unknown

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K318- Other specified diseases of stomach and duodenum

Interventions

Intervention1: Buprenorphine(Intravenous route): Injection Buprenorphine 0.3mg diluted with 10ml NS given intravenously in patients undergoing abdominal surgeries under general anaesthesia Control Int

Eligibility

Inclusion criteria

Inclusion criteria: 1. Consent to participate in study 2. ASA grade I & II 3. Patients scheduled for abdominal surgery

Exclusion criteria

Exclusion criteria: 1. Uncooperative patient/not able to understand pain assessment test 2. History of allergy or sensitivity or any other reaction to the study drug 3. History of any significant neurological, pulmonary, cardiovascular, hepatorenal, psychiatric, metabolic disease 4. parturient and lactating women 5. Bleeding diathesis

Design outcomes

Primary

Measure	Time frame
Epidural Buprenorphine provides better quality and prolonged duration of analgesia postoperativeTimepoint: 24weeks	—

Secondary

Measure	Time frame
Buprenorphine is better narcotics and produces less side effects as compared to other opioidsTimepoint: 24weeks	—

Countries

India

Contacts

Public ContactDR YOUVARAJ M

GAJRA RAJA MEDICAL COLLEGE

drjagrawal@gmail.com9300009942

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026