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A comparison of three different devices to provide 100% oxygen in critically ill patients just prior to intubation

A comparison of preoxygenation with Non Invasive Ventilation versus HFNO or Bag-valve mask prior to intubation in ICU patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046478
Enrollment
60
Registered
2022-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: Preoxygenation prior to intubation: Preoxygenation will be done in semi recumbant position 30°, for 3 to 5 minutes using either of the three methods selected by randomization. Control

Sponsors

Goa Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring intubation with acute hypoxaemic respiratory failure according to the following criteria : Respiratory rate more than 25 breaths per minute, or signs of respiratory distress, with a partial pressure of oxygen to FiO2 ratio equal or below 300mmHg

Exclusion criteria

Exclusion criteria: Intubation for cardiac arrest, Contraindications to non invasive ventilation (recent laryngeal, oesophageal or gastric surgery, facial fractures), Pregnancy

Design outcomes

Primary

MeasureTime frame
To record minimal oxygen saturation indicated by SpO2 during the intubation procedure.Timepoint: The minimum SpO2 will be noted within the first 5 minutes after intubation and within the first 30 minutes after intubation.

Secondary

MeasureTime frame
To record adverse events like hypotension, arrhythmia, aspirationTimepoint: Presence of severe hypotension (systolic blood pressure less than 65mmHg recorded at least once or less than 90mmHg lasting for 30 minutes despite treatment) or arrhythmias upto 30 minutes after intubation will be recorded Aspiration will be evaluated by taking a chest xray 48 hours after intubation.

Countries

India

Contacts

Public ContactDr Rohini Bhat Pai

Goa Medical College and Hospital, Bambolim, Goa

rohinivpai@gmail.com7741866436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026