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Is serum CA 72-4 level better than CEA and CA 19-9 in monitoring gastric cancer treatment

Comparing clinical utility of serum CA 72-4 level with CEA and CA 19-9 in monitoring gastric cancer treatment.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/10/046470
Enrollment
246
Registered
2022-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C169- Malignant neoplasm of stomach, unspecified

Interventions

None listed

Sponsors

Abbott India Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Histopathology confirmed, newly diagnosed and previously untreated gastric cancer patients

Exclusion criteria

Exclusion criteria: Past or present history of any other cancer, gastric surgery treatment history, severe functional impairment of important organs such as the heart, brain, lung, kidney or liver

Design outcomes

Primary

MeasureTime frame
Sensitivity, specificity and positive and negative predictive value of serum CA 72-4, CEA and CA 19-9 will be assessed in the diagnosis of gastric cancer recurrence, at the end of follow-up period of 2 yearsTimepoint: All the patients who are newly diagnosed of gastric cancer and planned to receive treatment as per existing disease management protocol will be followed up for 2 year and their serum tumor marker levels will be analyzed at every follow up to monitor the treatment and assess the disease progression.

Secondary

MeasureTime frame
Serum CA 72-4, CEA and CA 19-9 levels will be correlated with the imaging performed at baseline and during follow-up as per the existing disease management protocol and routine practice to check for gastric cancer recurrence.Timepoint: All the patients who are newly diagnosed of gastric cancer and planned to receive treatment as per existing disease management protocol will be followed up for 2 year and their serum tumor marker levels will be analyzed at every follow up and correlated with imaging findings wherever applicable, to monitor the treatment and assess the disease progression.

Countries

India

Contacts

Public ContactDr Shrikant Raut

Tata Memorial Hospital

rautsc@tmc.gov.in7718910464

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026