Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
Intervention1: myoinositol: Myoinositol 2000 mg + folic acid 200µg once daily for 12 weeks
Intervention2: metformin plus folic acid: metformin 500 mg three times daily plus folic acid 500 mcg once da
Sponsors
AARUPADAI VEEDU MEDICAL COLLEGE AND HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: Women in age group of 18 to 35 years with PCOS as per Rotterdam’s criteria patients of naïve PCOS with or without infertility.
Exclusion criteria
Exclusion criteria: Known case of PCOS who is already on any treatment for PCOS/infertility for past 3 months. Patient with galactorrhea and clinically diagnosed and known case of Cushing syndrome. Patients detected with presence of abnormal ovarian cyst. History of hormonal pills intake for the duration of past 3 months. Pregnancy Patients with type 2 DM
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin resistance (HOMA-IR) Polycystic ovarian morphology Hyperlipidemia Hyperandrogenism Timepoint: 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| • To study the side effects of myo-inositol plus folic acid, metformin plus folic acid and metformin. • To compare the side effects of the medication used in all the three groups. • To compare rate of conception in infertile women with PCOS in all three groups. • To compare cost effectiveness of the treatment options all three groups. Timepoint: in 12 weeks comparison | — |
Countries
India
Contacts
Public ContactDR PUSHPA KOTUR
AARUPADAI VEEDU MEDICAL COLLEGE AND HOSPITAL
Outcome results
None listed