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A comparative study of efficacy and safety of topical 0.05% tretinoin cream vs combination of canthex and topical 0.05% tretinoin cream in the treatment of acanthosis nigricans

A prospective comparative study of efficacy and safety of topical 0.05% tretinoin cream vs combination of canthex and topical 0.05% tretinoin cream in the treatment of acanthosis nigricans

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046450
Enrollment
60
Registered
2022-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80-L99- Other disorders of the skin and subcutaneous tissue

Interventions

Intervention1: Combination of canthex and topical 0.05% tretinoin cream: A detailed clinical examination will be done regarding the colour, texture and extent of lesions. Grading of the neck lesions w

Sponsors

SRM Medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient who have not taken treatment before for acanthosis nigricans Patients with lesions in the neck

Exclusion criteria

Exclusion criteria: Patients who are not willing for the study Pregnancy Patients who are currently on topical or systemic treatment for acanthosis nigricans Patients who are on treatment with topical or systemic retinods Patients on treatment with metformin Patient with lesions in regions other than the neck

Design outcomes

Primary

MeasureTime frame
To study the efficacy and effectiveness of topical 0.05% tretinoin cream and compare its efficacy with the combination of canthex and topical 0.05% tretinoin cream in the treatment of acanthosis nigricansTimepoint: 12 weeks

Secondary

MeasureTime frame
To determine the safety and side effects of topical tretinoin cream and canthex in patients with acanthosis nigricansTimepoint: 12 weeks

Countries

India

Contacts

Public ContactDeepthi R

SRM Institute of science and technology

muralin1@srmist.edu.in9840168711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026