It is a study done in lower limb surgeries to assess postoperative analgesia for 24hours. The study is done to assess and compare the efficacy of epidural magnesium sulphate with and without bupivacaine .

A Comparative study between epidural Bupivacaine with and without Magnesium sulphate for post operative analgesia in Lower limb surgeries.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046448

Enrollment

Registered

2022-10-13

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: M848- Other disorders of continuity of bone

Interventions

Intervention1: nil: nil Control Intervention1: group A - Bupivacaine With normal saline : Bupivacaine is a local anesthetic which inhibits NMDA receptor-mediated synaptic transmission in the dorsal h

Eligibility

Inclusion criteria

Inclusion criteria: 1.All patients posted for lower limb surgeries 2.Age group 18-60 years 3.Patients of American Society of Anaesthesiology grade 1 and 2

Exclusion criteria

Exclusion criteria: 1.Patients on any opioid or any sedative medication in the weak prior to the surgery 2.Patients with history of alcohol or drug abuse 3.Patients who have known allergies to any of test drugs 4.Patients with coagulation disorders or on anticoagulant drugs 5.Patients with cardiac disease[heart block,premature ventricular contractions,significant bradyarrhythmias,left ventricular failure] 6.Patients with respiratory distress 7.Containdications to epidural anaesthesia

Design outcomes

Primary

Measure	Time frame
1.vitals in post operative period 2.scoring of pain 3.any side effects in post operative period 4.Duration of post-operative analgesiaTimepoint: from time of completion of surgery till 24hrs post-operatively	—

Secondary

Measure	Time frame
Side effects in post-operative periodTimepoint: from time of completion of surgery till 24hrs post-operatively	—

Countries

India

Contacts

Public ContactDr Sadiya Lubna

Mahadevappa Rampure Medical College,Kalaburagi

nandyalnanda@gmail.com9663420776

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026