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A study comparing ability of palanosetron and ondansetron with dexamethasone in preventing post operative vomiting after laparascopic surgeries

A Comparative study on efficacy of intravenous palonosetron versus ondansetron and dexamethasone combination as a prophylaxis for prevention of postoperative nausea and vomiting after laparoscopic surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046442
Enrollment
60
Registered
2022-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Palonosetron: Palanosetron 0.075mg i.vadministered 3minutes before induction and incidence of postoperative nausea and vomiting will be observed for 48hours Control Intervention1: Ondan

Sponsors

Sri Venkateswaraa medical college hospital and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who give valid inform consent and willing to participate in the study 1) ASA grade I/II patients 2) age group of 18 to 60 years scheduled to undergo elective laparoscopic surgeries, under general anaesthesia.

Exclusion criteria

Exclusion criteria: Patient refusing to participate in the study 1) Any contraindication to the use of drug 2)BMI >35kg/m2 3) ASA III or more, 4) emergency procedure 5) Pregnant and lactating patients • Patients with history of motion sickness • Patients on steroid therapy, antiemetics or on treatment with other medication known to produce nausea and vomiting

Design outcomes

Primary

MeasureTime frame
asses incidence of post operative nausea and vomitting for 48 hoursTimepoint: 0mins,30mins,60mins,2hrs,4hrs,6hrs,8hrs,10hrs,12hrs,16hrs,20hrs,24hrs,36hrs,48hrs

Secondary

MeasureTime frame
requirement of rescue anti emeticTimepoint: 48 hours post operative period

Countries

India

Contacts

Public ContactArthiA

Sri Venkateswaraa medical college hospital and research center

drarthimd@gmail.com7895683205

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026