To compare the hemodynamic changes for phenylephrine and glycopyrrolate drugs after spinal anesthesia in pregnant patients posted for lower segment caesarean section

Comparison of hemodynamic changes between phenylephrine and glycopyrrolate group after spinal anesthesia for caesarean delivery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046431

Enrollment

Registered

2022-10-13

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: comparison of phenylephrine and glycopyrrolate after spinal anesthesia for caesarean delivery: comparison of hemodynamic responses of parturient during cesarean delivery Intervention2:

Eligibility

Inclusion criteria

Inclusion criteria: Parturients belonging to ASA 1 and 2 Age 20 to 35 years

Exclusion criteria

Exclusion criteria: Patients with cardiovascular disease Patients with cerebrovascular disease Pregnancy related hypertensive disease and diabetes mellitus Height less than 150cms or more than 180cms Weight less than 50kg or more than 100kgs Known fetal abnormalities Contraindications to glycopyrrolate Fever Twin pregnancies

Design outcomes

Primary

Measure	Time frame
1.TO study and compare the severity of hypotension and bradycardia in parturients undergoing caesarean section under spinal anesthesia 2.And to study and compare the side effects nausea and vomitingTimepoint: 1. maternal data such as age , BMI , baseline heart rate (HR) , systolic and diastolic blood pressure (SBP,DBP) , mean arterail pressure (MAP) 2. HR,SBP,DBP measured for 15mins after induction of subarachnoid block . 3.incidence if hemodynamic adverse effects.	—

Measure

Time frame

1.TO study and compare the severity of hypotension and bradycardia in parturients undergoing caesarean section under spinal anesthesia 2.And to study and compare the side effects nausea and vomitingTimepoint: 1. maternal data such as age , BMI , baseline heart rate (HR) , systolic and diastolic blood pressure (SBP,DBP) , mean arterail pressure (MAP) 2. HR,SBP,DBP measured for 15mins after induction of subarachnoid block . 3.incidence if hemodynamic adverse effects.

—

Secondary

Measure	Time frame
Nil Timepoint: Nil	—

Countries

India

Contacts

Public ContactMooli Pranisha

krishna institute of medical sciences

naseemakanase@yahoo.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026