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Comparing the bone regeneration capacity along with different clinical criteria of xenograft and simvastatin

Comparative evaluation of effect of simvastatin and xenograft (sticky bone) in third molar socket after surgical removal of impacted mandibular third molar

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046426
Enrollment
44
Registered
2022-10-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Placement of Sticky bone (xenograft which is derived from different species) in mandibular third molar extraction socket: Placement of sticky bone as a topical application with cgf memb

Sponsors

Punjab Government Dental College and Hospital Amritsar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA 1) All healthy patients aged 18-45 years with bilaterally symmetrical mandibular third molar impaction (partial or complete bony impactions) 2) Patients falling in the ASA class 1 and class 2. 3) Patients with no associated pathology with the concerned tooth 4) Patients with normal TMJ function. 5) Patients without any destructive habits such as smoking, chewing tobacco etc.

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA ? Patients with history of any drug allergy or allergy to any biomaterial to be used in the procedure or with a history of intake of any drug which may alter physiologic healing. ? Patients with history of chemotherapy or radiotherapy ? Patients who are pregnant, lactating or on oral contraception ? Patients having any pathology or infection with concerned tooth ? Patients with complications like root/crown fracture, alveolar or mandible fracture. ? Patients with intact walls of third molar sockets after extraction.

Design outcomes

Primary

MeasureTime frame
Following are the parameters on which simvastatin and sticky bone are compared after removal of mandibular third molar removal 1) pain 2) swelling 3) gingival index 4) bone density and regenerationTimepoint: Following are the parameters on which simvastatin and sticky bone are compared after removal of mandibular third molar removal 1) pain at 1 week, 1 month and 3 month 2) swelling 1 week, 1 and 3 month 3) gingival index at 1 week, 1 and 3 month 4) bone density and regeneration at 1 month and 3 month

Secondary

MeasureTime frame
Not applicableTimepoint: Not applicable

Countries

India

Contacts

Public ContactNitin verma

Bharat Petroleum Petrol Pump, Verka Industrial Area

Nitinvermagdc@gmail.com9814164068

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026