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To compare the onset and recovery time of minimal flow sevoflurane and desflurane anaesthesia.

Comparative evaluation of onset and recovery characteristics of minimal flow Sevoflurane and Desflurane anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046418
Enrollment
48
Registered
2022-10-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Desflurane: Minimal flow anaesthesia at 0.5l/min using desflurane after acheiveing MAC of 0.9 Control Intervention1: Sevoflurane: Minimal flow anaesthesia using sevoflurane at flow rate

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years 2. ASA physical status 1 and 2 3. Duration of surgery >1 hour

Exclusion criteria

Exclusion criteria: 1. History of hepatic,renal,or cardiovascular disease 2.Patient with chronic obstructive pulmonary disease 3. Pregnant patient 4.Obesity (BMI >30kg/m2)

Design outcomes

Primary

MeasureTime frame
1.Onset time 2.Recovery timeTimepoint: 1.time in seconds after intubation to acheive MAC of 0.9 2.time in seconds after vaporizer closure to eye opening

Secondary

MeasureTime frame
1.systolic blood pressure, diastolic blood pressure, heart rate and Spo2 2.Bispectral index 3.end tidal carbon dioxide concentration 4.Anaesthetic agent consumption 5.carbon dioxide equivalents Timepoint: 1.Baseline reading and after 5,10,15,30 minutes of induction and after 30 minutes thereafter

Countries

India

Contacts

Public ContactDR MEGHA RANJAN

Maulana Azad Medical college

munisha.agarwal@gmail.com9968604216

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026