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A comparative study on efficacy of CO2 laser and topical 2% clotrimazole daily application versus Nd: YAG laser and topical 2% clotrimazole daily application with lasers given at interval of 3 weeks to maximum of 6 sessions in treatment of onycomycosis

A comparative study on efficacy of CO2 laser and topical 2% clotrimazole versus Nd: YAG laser and topical 2% clotrimazole in treatment of onycomycosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046393
Enrollment
50
Registered
2022-10-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A00-B99- Certain infectious and parasitic diseases

Interventions

Intervention1: Co2: CO2 laser 110mj/ cm2 along with topical 2% clotrimazole daily night application Control Intervention1: Nd:YAG: Nd: YAG laser at dose of 750 mj/cm2 along with topical 2% clotrimazol

Sponsors

Chengalpattu medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: CLINICAL DIAGNOSIS OF ONYCOMYCOSIS

Exclusion criteria

Exclusion criteria: 1.PREGNANT AND LACTATING WOMEN 2.PATIENTS WITH CHRONIC KIDNEY DISEASE,ON IMMUNOSUPPRESSUVE DRUGS.

Design outcomes

Primary

MeasureTime frame
efficacy of CO2 laser and topical 2% clotrimazole versus Nd: YAG laser and topical 2% clotrimazole in treatment of onycomycosisTimepoint: At baseline,6 week of treatment, 3 months after treatment—

Secondary

MeasureTime frame
safety of CO2 laser and topical 2% clotrimazole versus Nd: YAG laser and topical 2% clotrimazole in treatment of onycomycosisTimepoint: At each session of treatment- 3 week ,6 week ,9 week ,12 week,15 week ,18 week—

Countries

India

Contacts

Public ContactDR R Sindhuja

CHENGALPATTU MEDICAL COLLEGE AND HOSPITAL

nivesekhar@gmail.com9486914293

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026