Clinical and laboratory examination of dental plaque in hospitalised children treated topically with olive oil, olive oil with white turmeric, and olive oil with neem

Clinical and Microbiological Evaluation of Dental Plaque on topical application of Olive oil, Olive oil with 35% Curcuma zedoaria and Olive oil with 30% Azadirachta indica in hospitalized children: A Randomised Clinical Study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/10/046385

Enrollment

Registered

2022-10-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D509- Iron deficiency anemia, unspecified

Interventions

Intervention1: Extra virgin olive oil: Extra virgin olive oil(100) 2ml twice daily for 3 days Intervention2: Azadirachta indica with olive oil: Azadirachta indica with olive oil (30:70 v/v) 2ml twice

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children from 3-14 years of age. 2. Children hospitalized for a minimum period of 4days 3. Non ambulatory hospitalized children who cannot brush/expectorate

Exclusion criteria

Exclusion criteria: 1. Children who did not give assent 2. Children whose Parents did not give consent 3. Children using oxygen mask 4. Children in ventilator 5. Children in ICU - high risk 6. Children having allergy to Azadirachta or Curcuma

Design outcomes

Primary

Measure	Time frame
The synergistic impact of two herbal oils can reduce plaque, bacterial and fungal growth. The microbial load (Streptococcus mutans, Lactobacillus and Candida albicans) and accumulation of dental plaque would be reduced.Timepoint: Clinical and microbiological response after 24, 48 and 72 hours	—

Secondary

Measure	Time frame
The palatibilty of the product by the patient by Likert scaleTimepoint: Baseline, after 24, 48 and 72hours	—

Countries

India

Contacts

Public ContactSimron Baishya

K M Shah Dental College

dranshula@gmail.com7600916400

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026