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A study to evaluate the preoperative blood markers influencing the outcomes in patients of Pancreatic cancer

Association of preoperative systemic inflammation markers in patients with pancreatic cancer with short and long-term outcomes (SIIPC study) - SIIPC study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/10/046383
Enrollment
400
Registered
2022-10-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C25- Malignant neoplasm of pancreas

Interventions

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients who underwent elective pancreatic cancer surgery (if curative) in TMH during the time period Jan 2017 to Dec 2019. 2.Patients who have received NACT and or RT prior to surgery.

Exclusion criteria

Exclusion criteria: 1.All inoperable cases during the study period. 2.Patients who have preoperative clinical evidence of non hepato-biliary source of infection or other chronic inflammatory conditions like arthritis, SLE, etc. will be excluded from the study. 3.Patients on treatment with steroids. 4.Patients with psychiatric disorders on treatment with medications. 5.Patients on therapeutic heparin within 10 days before surgery.

Design outcomes

Primary

MeasureTime frame
1.To study role of preoperative systemic inflammatory markers (CRP, albumin, NLR, PLR, PNI, SII, and mGPS) to predict major postoperative complications (Clavien Dindo Grade 3-5) at discharge in patients operated for pancreatic cancer surgery.Timepoint: Until discharge from hospital

Secondary

MeasureTime frame
To determine the predictive value of: 1.Preoperative systemic immune inflammatory markers (CRP, albumin, NLR, PLR, PNI, SII, and mGPS) on 3-year overall survival, and disease free survival. 2.Modified GPS for postoperative infectious complication.Timepoint: At 3 years

Countries

India

Contacts

Public ContactDr Badrinath Pandhrinath Katre

Tata Memorial Hospital

vandanachaukar@hotmail.com02224177042

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026