FindTrial
Sign In

Does surgery Stop the wear and tear of the knee joint

â??Is Open Wedge-High Tibial Osteotomy (OW-HTO) alone or combined root repair with Open Wedge-High Tibial Osteotomy retard the progression of osteoarthritis and improve outcome? Randomised controlled trial -non-operative root tear (control) versus Open Wedge-High Tibial Osteotomy alone versus root repair with Open Wedge-High Tibial Osteotomy.â?? - OW-HTO, MMRR

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046359
Enrollment
100
Registered
2022-10-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Open Wedge-High Tibial Osteotomy and combined root repair with: Pre-arthritic knee (root tear with varus aligned knee) are randomised into 3 groups, OW-HTO group (alignment correction s

Sponsors

Ganga medical centre and hospital PVT LTD
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pre arthritic knee (posterior horn meniscal root tear with varus aligned knee greater than 5degrees) 2. Localized posteromedial joint line tenderness with confirmation of MMPRT on MRI 3. Varus aligned knee >5 degrees 4. KL grades 1,2,3 on a standing knee anteroposterior (AP) x-ray radiograph

Exclusion criteria

Exclusion criteria: 1. Varus aligned knee more than10 2. KL grade greater than grade3 3. Patellofemoral arthritis 4. Cruciate/collateral ligament insufficiency 5. SPONK (Spontaneous osteonecrosis of the knee) 6. BMI more thAN 30

Design outcomes

Primary

MeasureTime frame
The clinical outcomes will be assessed in functional scores (Visual Analogue scale (VAS) scores, Knee injury Osteoarthritis Outcome Scores(KOOS), International knee documentation committee scores (IKDC)& Tegner Lysholm scores), radiological outcomes (Xray assessment -Hip-Knee-Ankle (HKA) Axis, Medial Proximal Tibial Angle(mPTA), Kellgren Lawrence (KL) grading. MRI assessment:Medial meniscus extrusion/Relative percentage of extrusion correction, healing of meniscus) for all the groups and second-look arthroscopy findings for operative groups.Timepoint: Patients will be followed up at 6 weeks, 3 months, 6 months, 1 year, 18 months, 24 months and yearly intervals then after.—

Secondary

MeasureTime frame
second look arthroscopy to assess loss of cartilage lesion grade 1 to 4 on ICRS scale, and meniscal healing as Complete healing, Lax healing, Scar tissue, Failed healing.Timepoint: A second look arthroscopy will be planned at 24 months.—

Countries

India

Contacts

Public ContactSilvampatti Ramasamy Sundararajan

Ganga Hospital

sundarbone70@hotmail.com09843256545

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026