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Comparing antibacterial action and in between appointment pain of herbal irrigant versus 3% sodium hypochlorite as root canal irrigant in lower molars.

“Comparative evaluation of antimicrobial efficacy and inter-appointment pain of Triphala versus 3% sodium hypochlorite as root canal irrigant in mandibular molars with necrotic pulps- A Randomized Clinical Study ?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046344
Enrollment
40
Registered
2022-10-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Triphala: To evaluate the anti-microbial efficacy of Triphala as root canal irrigant in mandibular molars with necrotic pulp using bacterial colony forming units. Control Intervention

Sponsors

Shreya Volety
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy patients (Category: American Society of Anesthesiologists class 1) (ASA House of Delegates 2014) aged between 18–60 years with mandibular (first and second) molar teeth diagnosed with pulp necrosis with or without apical periodontitis. 2. Necrotic pulps as confirmed by negative response to sensitivity pulp tests. 3. Patients with mandibular teeth with or without periapical radiolucency size 4. A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study.

Exclusion criteria

Exclusion criteria: 1. Patients suffering from a significant systemic condition. 2. Patients who received antibiotic therapy within the previous 3 months 3. Teeth with the calcified pulp chamber 4. Teeth that had received previous endodontic treatment 5. Cases showing periodontal pockets deeper than 4mm. 6. Patients on medications such as chemotherapy, anticoagulants, corticosteroids, bisphosphonates and immunosuppressant drugs

Design outcomes

Primary

MeasureTime frame
The result of this study will help us to know about the antimicrobial efficacy of Triphala as a root canal irrigantTimepoint: baseline, 6hrs, 12hrs, 24hrs, 48hrs

Secondary

MeasureTime frame
To know about the inter-appointment pain of Triphala versus 3% sodium hypochlorite as root canal irrigant in mandibular molars with necrotic pulpTimepoint: within 7 days

Countries

India

Contacts

Public ContactDr Kishan KV

K.M Shah Dental College and Hospital

drkishankv@yahoo.co.in08141787335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026