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Comparing the efficacy of Esmolol versus Magnesium sulphate for attenuation of cardiovascular response to laryngoscopy and intubation.

Attenuation of cardiovascular response to laryngoscopy and intubation : A comparative study between Esmolol and Magnesium sulphate

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046271
Enrollment
80
Registered
2022-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: laryngoscopy and intubation: During laryngoscopy and intubation - stress response is seen. Decreasing this response with esmolol 1.5mg/kg body weight intravenously bolus given 3mins pr

Sponsors

Dr Pinnamaneni Siddhartha Institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective surgeries. 2. Age between 18 and 60 years of both the sexes. 3. Patients with ASA Grade I or II. 4. Mallampati airway assessment of Grade I, II

Exclusion criteria

Exclusion criteria: 1.Unwilling Patient 2.Emergency Surgeries 3.patients anticipated difficult for laryngoscopy and intubation 4.Patients with Mallampati airway assessment of grade 3,4. 5.Patients with ASA Grade III or IV. 6.Patients previously on beta blockers or Calcium Channel blockers or sympatholytic drugs.

Design outcomes

Primary

MeasureTime frame
Attenuated Cardiovascular changes- decreased HR,BPTimepoint: baseline,1min,2mins,5mins and 10 mins

Secondary

MeasureTime frame
decreased intubation response -Cardiovascular changes like HR,bp and rate pressure productTimepoint: baseline,1min,2mins,5mins,10 mins

Countries

India

Contacts

Public ContactD Gnana Prashanthi

MBBS MD ANAESTHESIA PDCC CARDIAC ANAESTHESIA

drshankar1811974@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026