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Markers of outcome of heart bypass surgery

Whether plasma nitric oxide alone or in combination with other markers of ischemia and inflammation predicts the outcome of Coronary Artery Bypass grafting (CABG) : A proof of concept study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/10/046266
Enrollment
6
Registered
2022-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

None listed

Sponsors

Department of Science and Technology and Renewable Energy, Chandigarh Administration
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Any patient who is screened for Coronary artery bypass grafting (CABG) at PGIMER, Chandigarh

Exclusion criteria

Exclusion criteria: Emergency surgery

Design outcomes

Primary

MeasureTime frame
It is expected that the boimarkers of ischemia and inflammation will predict the hemodynamic performance of the patients undergoing coronary artery bypass grafting during the stay in the hospital. The markers of ssutdy are CK MB, TROPONIN I, D DIMER, MYOGLOBIN, BNP, PLASMA NITRIC OXIDE, ISCHEMIA MODIFIED ALBUMIN measured 0 hr, during aorta cross clamp , at the end of cardiopulmonary bypass, 6 hrs, 12 hrs, 24 hrs and 48 hrs post surgery. These parameters will be compare among themselves and with the hemodynamic parameters to predict the outcome of the surgery.Timepoint: It is expected that the boimarkers of ischemia and inflammation will predict the hemodynamic performance of the patients undergoing coronary artery bypass grafting during the stay in the hospital. The markers of ssutdy are CK MB, TROPONIN I, D DIMER, MYOGLOBIN, BNP, PLASMA NITRIC OXIDE, ISCHEMIA MODIFIED ALBUMIN measured 0 hr, during aorta cross clamp , at the end of cardiopulmonary bypass, 6 hrs, 12 hrs, 24 hrs and 48 hrs post surgery. These parameters will be compare among themselves and with the hemodynamic parameters to predict the outcome of the surgery.

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactRUPESH KUMAR

POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH, CHANDIGARH

rkctvs@gmail.com9883690388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026