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A Comparison of two drugs (oral clonidine and metoprolol) in terms of effect of BP, Heart rate and bleeding, during surgery of nose under anaesthesia

A Comparison of effects of oral premedication with clonidine and metoprolol on intraoperative haemodynamics and surgical conditions during functional endoscopic sinus surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046238
Enrollment
68
Registered
2022-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified Health Condition 2: O- Medical and Surgical Health Condition 3: J339- Nasal polyp, unspecified

Interventions

Intervention1: oral clonidine and metoprolol: tab clonidine 300 mcg and tab metoprolol 50 mg orally 2 hr before surgery Control Intervention1: tab clonidine: tab clonidine 300 mcg 2 hr before surgery

Sponsors

Department of anaesthesiology Maharana Bhoopal government hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 or 2 Normotensives or treated hypertensives undergoing FESS surgery

Exclusion criteria

Exclusion criteria: ASA grade 3 or higher Uncontrolled asthmatic Diabetic Asthmatic Pregnant mothers

Design outcomes

Primary

MeasureTime frame
Haemodynamics Timepoint: Intraoperative (120 min)

Secondary

MeasureTime frame
Side effectsTimepoint: intraoperative (1-2hr)

Countries

India

Contacts

Public ContactDr Priya Verma

RNT medical college udaipur

drlalitkumar@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026