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comparison of dexmedetomidine infusion and diltiazem infusion in blunting laryngoscopic response in patients undergoing surgery under general anaesthesia

comparison of intravenous dexmedetomidine infusion with intravenous diltiazem infusion to attenuate haemodynamic responses to laryngoscopy and endotracheal inbtubation in adult patients undergoing general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046221
Enrollment
120
Registered
2022-10-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: intravenous dexmedetomidine infusion and intravenous diltiazem infusion: Patients receiving normal saline infusion will be in group 1 Patients receiving dexmedetomidine infusi

Sponsors

ABVIMS and DrRML hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA(American society of anaesthesiologists) grade 1,planned for surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Hypertensive patients Previous history of coronary artery disease History of arrhythmias, pacemakers Renal/hepatic dysfunction Chronic obstructive lung disease Patients allergic to dexmedetomidine and/or diltiazem Usage of beta blockers Emergency surgeries Full stomach patients Pregnant and paediatric patients

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure, Diastolic blood pressure, Mean arterial pressure and heart rateTimepoint: Baseline recording followed by Each minute for ten minutes after induction of anesthesia and laryngoscopy and intubation

Secondary

MeasureTime frame
Bradycardia and hypotensionTimepoint: Baseline recordings followed by Every minute till ten minutes after induction of anaesthesia laryngoscopy and intubation

Countries

India

Contacts

Public ContactVIJAY KUMAR NAGPAL

ABVIMS and Dr.RML hospital

nagpalvijaykumar@gmail.com9968304240

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026