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A Drug Named Dexmedetomidine Will Be Used In Inhalational Form Into Your Breathing System To Blunt The Stress Response Which Occurs While Putting A Tube Through The Mouth Into The Breathing System Before Surgery

Effect Of Preoperative Dexmedetomidine Nebulization in Controlling Postintubation Haemodynamic And Stress Response In Adults Undergoing Elective Surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046174
Enrollment
120
Registered
2022-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Nebulized Dexmedetomidine: Nebulized Dexmedetomidine will be given preoperatively to blunt the stress response to intubation Control Intervention1: Nebulization with Normal Saline: Pati

Sponsors

VMMC AND SAFDARJUNG HOSPITAL
Lead Sponsor
Dr Ameeta Sahni
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Adults of age group from 18 to 65 years undergoing elective surgeries ASA grade 1 patients

Exclusion criteria

Exclusion criteria: Age group less than 18 years and more than 65 years History of hypersensitivity to Dexmedetomidine Pregnancy Patient on psychiatric medications, on steroid therapy

Design outcomes

Primary

MeasureTime frame
Change in Haemodynamic parameters such as heart rate, Blood pressure,Mean arterial pressure.To determine cortisol levels 10minutes post intubationTimepoint: Measurement of heart rate, Blood pressure, Mean arterial pressure at 0,3,5,10 minutes after intubation. Measurement of cortisol levels at 10 minutes after intubation—

Secondary

MeasureTime frame
To determine cortisol levels 10 minutes post intubationTimepoint: Measurement of cortisol levels at 10 minutes after intubation—

Countries

India

Contacts

Public ContactDr Krishna S

Vardhman Mahavir Medical College and Safdarjung Hospital

ameetaas@yahoo.com9811201585

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026