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TO SEE WHETHER GIVING PHENYLEPHRINE A DRUG WHICH RISES THE BLOOD PRESSURE PROPHYLACTICALLY TO COMBAT HYPOTENSION CAUSED BY PROPOFOL WHICH IS ROUTINELY USED AS INDUCTION AGENT IN GENERAL ANAESTHESIA

TO STUDY THE EFFICACY OF PROPHYLACTIC INTRAVENOUS PHENYLEPHRINE IN PROPOFOL INDUCED HYPOTENSION DURING INDUCTION OF GENERAL ANAESTHESIA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/10/046103
Enrollment
150
Registered
2022-10-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS- Health Condition 2: 1- Obstetrics Health Condition 3: 1- Obstetrics Health Condition 4: 1- Obstetrics Health Condition 5: R108- Other abdominal pain

Interventions

Intervention1: Group C Control will be receiving normal saline. after 5min of induction: Induction of general anaesthesia is done with 1.5 ââ?¬â?? 2 mg / kg of propofol, 1.5 ââ?¬â?? 2mg of succinyl

Sponsors

Dr Rashmee Vijay Chavan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) American society of Anesthesiologists (ASA) grade 1and 2 2) Patients of age 18 to 60 years of any gender 3) Undergoing elective surgeries under general anaesthsesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: 1) Patient not giving consent 2) Patients with Ischemic Heart Disease(IHD) 3) Patient with cardiac conduction block. 4) Uncontrolled hypertension 5) Patient with allergies to any drug 6) Cases with expected Difficult intubation 7) Pheochromocytoma 8) Patients with BP more than 180/100 mm hg after intubation.

Design outcomes

Primary

MeasureTime frame
1) To measure SBP DBP MAP and PR after induction of anaesthesia in control group. 2) To measure SBP DBP MAP and PR after induction of anaesthesia in study group. 3) Comparison of these hemodynamic parameters in both the groups (test and control group) for any statistical significance. Timepoint: 1) After 5 min of intubation 2)after 10 min of intubation 3) after 15 min of intubation—

Secondary

MeasureTime frame
Any bradycardia or hypotension will be noted afterTimepoint: For next 15min—

Countries

India

Contacts

Public ContactDr SAHANA N

DYPatil Medical College, Kolhapur

rashmeevchavan@rediffmail.com9823243848

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026