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Comparative study to evaluate the pain relieving effect of two drug mixtures -bupivacaine with buprenorphine and bupivacaine with dexmedetomidine in ultrasound guided chest wall muscle plane block in patients undergoing breast cancer surgeries

Comparative study to assess the analgesic effect of bupivacaine with buprenorphine and bupivacaine with dexmedetomidine in ultra sound guided pectoral nerve block type 2 in modified radical mastectomy surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/046092
Enrollment
46
Registered
2022-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E08-E13- Diabetes mellitus Health Condition 2: I10-I16- Hypertensive diseases Health Condition 3: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: ULTRASOUND GUIDED PECTORAL BLOCK TYPE 2: INJ.Bupivacaine 0.5 % 0.2 ml per kg with INJ Dexmedetomidine 1 microgram per kg Control Intervention1: ULTRASOUND GUIDED PEC BLOCK TYPE 2: INJ.B

Sponsors

ESIC Medical College and PGIMSR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for modified radical mastectomy suregeries ASA I ASA II ASA III

Exclusion criteria

Exclusion criteria: 1)Known allergy to local anaesthetics 2)Patient refusal 3)Contraindications to regional anaesthesia (bleeding diathesis, use of any anti-coagulants, infection at the site of injection) 4)Patients on beta-blockers 5)Severe kidney disease, liver disease , seizure disorder and cardiovascular disease 6)Chest wall deformity or pathology 7)ASA IV

Design outcomes

Primary

MeasureTime frame
i.Time to first rescue analgesia post operatively ii.Variation in HR, NIBP, MAP post block in the patients intraoperatively Timepoint: 1.Time to rescue analgesia assessed for about 24 hrs to 36 hrs after surgery 2.Variation in HR,NIBP,MAP assessed every 15 minutes intra operatively

Secondary

MeasureTime frame
i.The amount of analgesics used in 24 hrs ii.Pain assessment using VAS scale Timepoint: 24 to 36 hrs after surgery

Countries

India

Contacts

Public ContactDr Ilango Ganesan

ESIC Medical College and PGIMSR Chennai

gilang@rediffmail.com9884149429

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026