Health Condition 1: J189- Pneumonia, unspecified organism
Conditions
Interventions
Intervention1: Oral Zinc Supplementation: Children will be prescribed antibiotics and randomly allocated to receive 20 mg elemental zinc or placebo, in 2 doses per day to minimize adverse gastrointest
Sponsors
Vijayanagar Institute of Medical Sciences Ballari Karnataka
Eligibility
Inclusion criteria
Inclusion criteria: All children aged 2 months to 2 years diagnosed as having acute severe pneumonia and hospitalized will be included in the study after obtaining written informed consent from either of the parents. Acute Severe Pneumonia is defined in the study as a respiratory rate of 50/min, accompanied with crepitations on auscultation and the presence of any one of the following danger signs: lethargy, inability to feed, chest indrawing, or central cyanosis.
Exclusion criteria
Exclusion criteria: Children will be excluded if they had a history of chronic cardiac or renal disease, illness severe enough to require ventilation, malnutrition severe enough to require immediate nutritional rehabilitation therapy, illness requiring hospitalization in the previous 21 days, or current zinc supplementation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of hospitalization, Duration of Severe Pneumonia, Duration of Pneumonia, Duration of nil-per-oral, Duration of Intravenous fluids, Duration of oxygen use, Treatment failure requiring 2 nd or 3 rd line drugs.Timepoint: Duration of hospitalization, Duration of Severe Pneumonia, Duration of Pneumonia, Duration of nil-per-oral, Duration of Intravenous fluids, Duration of oxygen use | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment failure requiring 2 nd or 3rd line drugs, Recovery timeTimepoint: Treatment failure requiring 2 nd or 3rd line drugs, Recovery time | — |
Countries
India
Contacts
Public ContactSathiyanarayanan S
All India Institute of Medical Sciences (AIIMS), Mangalagiri
Outcome results
None listed